Stony Brook University SUNY Korea

Stony Brook University Hospital has received the American Heart Association’s Gold Plus Get With The Guidelines® Heart Failure Quality Achievement Award. The Gold Plus award, which Stony Brook has received for the third consecutive year, recognizes the hospital’s commitment to ensuring heart failure patients receive the most appropriate treatment according to nationally recognized, research-based guidelines grounded in the latest scientific evidence. The goal is speeding recovery and reducing hospital readmissions for heart failure patients.      “The award is a reflection of Stony Brook University Hospital’s commitment to excellence in heart failure care,” said Marc Goldschmidt, MD, director, Heart Failure and Cardiomyopathy Center and medical director, Ventricular Assist Device (VAD) Program at the Stony Brook University Heart Institute.      Cardiology Front Row: Hal Skopicki, MD, PhD; Anne Marie Berggren, RDN, MS, CDN, CNSC; Lauren Weiss, RN; Monica Fox, RN; Lauren Pilato, NP; Ann Marie, Schneider, Social Services; Edlira Tam, DO, Associate Medical Director, VAD Program; Michelle Weisfelner Bloom, MD, Director, Outpatient Heart Failure and Cardiomyopathy Center; Marc Goldschmidt, MD, Director, Heart Failure and Cardiomyopathy Center and Medical Director, VAD Program; Allison J. McLarty, MD, Surgical Director, VAD Program; Terri Springer, NP. Back Row: Philip Travaglia, RN, Clinical Documentation Specialist; Caitlin Borriello, NP; Jillian Fitzgerald, RN, VAD Coordinator; Nancy Utano, RN; Omar Blagrove, VAD Program Administrator; Peter Reilly, NP, VAD Coordinator; Stephen Handzel, RN, MS, Assistant Director, Nursing, Noninvasive Cardiology; Melissa Goldstein, RN “Research has shown that by adhering to clinical measures through the Get With The Guidelines quality improvement initiative, we can often see fewer readmissions and lower mortality rates,” added Edlira Tam, DO, associate director of the VAD Program at the Stony Brook University Heart Institute.     More than 6.5 million adults in the United States are living with heart failure. Many heart failure patients can lead a full, enjoyable life when their condition is managed with proper medications or devices and with healthy lifestyle changes.     “Being part of this initiative means that we continuously track our success in meeting evidenced-based clinical guidelines — all with the ultimate goal of delivering optimal outcomes for our patients,” said Hal Skopicki, MD, PhD, co-director, Stony Brook University Heart Institute and the Ambassador Charles A. Gargano Chief of Cardiology.      Michelle Bloom, MD, director, Cardio-Oncology Program and director, Heart Failure and Cardiomyopathy Center at the Stony Brook University Heart Institute, added “Comprehensive care of our heart failure patients requires an entire team including specialized nurses, nurse practitioners, coordinators, physicians and researchers who can not only diagnose advanced cardiology disease but are experts at determining its cause and providing cutting-edge care.”     Stony Brook University Hospital’s Gold Plus Get With The Guidelines®– Heart Failure Quality Achievement Award is significant as it is the highest of six levels of achievement – Gold Plus, Gold, Silver Plus, Silver, Bronze and Participating.

The Career Center’s annual Diversity Recruitment Networking Event attracted a record number of students as well as employers on Nov. 5, providing students a valuable opportunity to build connections with employers who are focused on diversity, equity, and inclusion in the workplace.     “The Career Center has been developing diversity recruitment initiatives and programs for twenty years,” said Director of Employer Engagement and Diversity Recruitment Kimberly Joy Dixon. “That is what makes this event so special, the opportunity for students to connect with companies and organizations who are dedicated to these efforts and who are building a space this generation is excited to work in.”     The event, now in its 14th year, had been traditionally held in person with about 25-30 employers, but the switch to virtual last year — combined with the increased focus on diversity and inclusion among companies and organizations who value diversity —  has led to a dramatic increase in participation. Close to 90 employers took part in the event this year, and all employers who attended have a diversity mission statement and ongoing diversity and inclusion efforts in the workplace and recruiting strategies.             Student attendance for the Diversity Recruitment Panel more than doubled last year’s total, with 157. Companies including Stony Brook University Hospital, Henry Schein, Moody’s, Societe Generale, Amazon, and PSEG spoke about the importance of diversity, equity, and inclusion, and how each of their companies create spaces for conversations around this topic. The panel was co-hosted by several student groups, including ColorStack, the National Society of Black Engineers (NSBE), Women in Computer Science (WiCS), C-STEP Club, Society for Women Engineers (SWE), Delta Sigma Pi, Latin American Student Organization (LASO) and Jubilé Latino.     The panel was followed by the Diversity Recruitment Job and Internship Fair, where students met with recruiters from more than 80 companies looking to hire Stony Brook talent; each company attending the fair has demonstrated a commitment to diversity. Students met one-on-one or in group virtual sessions with companies like GEICO, Canon USA, Northwell Health, Brookhaven National Laboratory, Moody’s, the U.S. Environmental Protection Agency, the Federal Bureau of Investigation, and many more.     Angel Velazquez ’22 “had a fantastic experience” attending the event. “I loved how employers were able to communicate how important diversity and inclusion are to them and how different perspectives have helped define their strategies in hiring equitably, and ensuring that their company provides an environment where people from all different backgrounds can be successful.”             “The Diversity Recruitment event opened my eyes to the progress companies are taking to make the workplace more diverse and inclusive,” said Destiny Dialene ’23.     Added Amaya McDonald ’22, “I realized the importance of diversity in the workplace and having an employer who values people’s differences.”     Employers who participated in the recruitment panel explained the importance of diversity to their companies.     “Part of diversity is bringing your whole self to work and being able to be welcomed in the totality of your experience,” said Irene Muldowney of PSEG. “There is a two-fold thing that needs to happen: Absolutely, we want the best of the best out there, that’s why we want to reach as many pools of talent as possible. But the second part of that is, once we get folks in, how do they feel? Are they going to stay? Do they want to stay?”     Added Dave Rodriguez of Henry Shein, “One of the important things is to be curious. Being curious drives learning. If we’re curious in our careers, it will be a healthy, long, successful one.”

The genomic revolution has enabled researchers to assess cell-by-cell genetic variations, but very few techniques exist to measure cell-by-cell metabolic variations, a more powerful way to understand cell responses to changing environmental conditions. Researchers from Stony Brook University’s School of Marine and Atmospheric Sciences (SoMAS), led by Professor Gordon T. Taylor, demonstrated that Raman microspectroscopy can accurately measure cell-by-cell variations in growth rates of the bacterium E. coli grown in a broth medium. They validated the Raman-based technique against independent traditional population-based spectroscopic and mass spectrometric measurements.     This montage, which is displayed on the cover of “Applied and Environmental Biology,” shows a bacterial cell population by way of a Raman microspectrophotometer and a measurement assimilation of carbon-13 of the population’s proteins. Detection of the carbon-13 enrichment in individual bacterial cells helps to calculate microbial growth rates at the single-cell level. Credit: T. Zaliznyak “The technique emerging from our laboratory can be applied to the study of free-living and host-associated microbiomes, which could prove crucial in understanding more about their functional responses to stressors,” said Taylor, director of the NAno Raman Molecular Laboratory (NARMIL) at SoMAS. “We also believe this is an enabling technology to examine individuality in cell populations and could have broad applications in microbiology, cell biology and biomedicine.”     Details of the technique and results are published in the American Society of Microbiology’s Applied and Environmental Microbiology. A visual of the technique is also highlighted on the cover of the journal edition.

On Thursday evening, November 4, The Fragrance Foundation (TFF) celebrated Virginia Bonofiglio, assistant professor and head of FIT’s undergraduate program in Cosmetics and Fragrance Marketing (CFM), and Stephan Kanlian, professor and head of the college’s graduate program in Cosmetics and Fragrance Marketing and Management (CFMM), for their outstanding work in education and in the beauty industry. They were inducted into the Fragrance Foundation Circle of Champions, which honors individuals within the fragrance industry who have made an exceptional impact over a significant period of time. This year marks the first time that educators have been recognized with this prestigious honor.     “We are absolutely delighted to recognize and celebrate the contributions and achievements of FIT’s Virginia Bonofiglio and Stephan Kanlian, whose dedication to training and instructing future leaders in the fragrance industry through academic purpose and innovation is truly unparalleled,” said Linda G. Levy, president of TFF.     The in-person dinner was carefully planned to bring approximately 180 people from the beauty and fragrance industries together safely, after two years of being remote with no in-person events.     Attendees included Dr. Joyce F. Brown, president of FIT; Robin Burns-McNeill, chair, FIT Board of Trustees, and co-founder of Battalure Beauty; Dr. Brooke Carlson, interim dean, School of Graduate Studies, FIT; Shannon Maher, interim dean, Jay and Patty Baker School of Business and Technology, FIT; Francisco Costa, Fashion Design ‘90, fashion designer and founder of Costa Brazil skin care; Tennille Kopiasz, CFMM ’04, CFM ’98, chief marketing officer, Fresh/LVMH; Crystal Sai, CFMM ’17, executive director and chief of staff, global online, Estée Lauder Companies; Linda Wells, founding editor-in-chief, Allure; and Laura Slatkin, executive chairwoman and founder, NEST Fragrances. Students from both programs were also on hand to celebrate professors Bonofiglio and Kanlian.     Interim Dean of the School of Graduate Studies Brooke Carlson, Head of CFMM Stephan Kanlian, FIT President Joyce F. Brown,  Head of CFM Virginia Bonofiglio, and Interim Dean of the Jay and Patty Baker School of Business and Technology.  Dr. Brooke Carlson, Stephan Kanlian, FIT President Joyce F. Brown, Virginia Bonofiglio, and Shannon Maher. FIT’s CFM and CFMM programs are the first of their kind. CFM was started in 1988 in response to industry demand. In 1993, FIT expanded its offerings further by opening the Annette Green Fragrance Foundation Studio, a fragrance development laboratory named in recognition of Green’s work on behalf of the program. Today, CFM has graduated many students who have gone on to lead successful careers in the beauty industry, both at global companies and as entrepreneurs who have launched their own businesses.      Dr. Brown’s remarks echoed Levy’s sentiment and gratitude for the evening’s honorees. “There is so much about these two beauty programs that exemplifies FIT and its history. Like the college itself, each one was founded by visionary industry leaders—leaders like yourselves who understood the value of education and the need for new and innovative thinking. FIT attracts what we like to call ‘unconventional thinkers’—the kinds of students who love to problem-solve, experiment, and explore. When you marry that kind of spirit with rigorous, forward-looking curricula and faculty leaders like Virginia and Stephan, industry is the ultimate beneficiary,” she said.      Tennille Kopiasz, an alum of both programs, spoke about her experiences. “Moving to NYC to live my dreams, I discovered the beauty industry that was far better than I ever could imagine,” she said. “You pushed me to not just work in an office internship, but to work behind a counter and touch the consumer. That is where I saw first-hand the transformational power and the confidence beauty gave women.”     “This jewel of a program was handed to me and I have been honored to grow the program and nurture its students for the last 11 years,” Bonofiglio said. “Our alumni are our greatest advertisement and a testament to all that an education at FIT has to offer. It is now, has been, and will always be about the students. If we are the educators, they will be the innovators, the disruptors, and the game changers who will propel this industry into the future. I want to thank them in advance for all they are going to do.”     CFMM was created in collaboration with industry as an innovative two-year leadership development program for outstanding emerging executives. Upon its inception in 2000, CFMM quickly became recognized as the beauty industry’s think tank, comprised of executives helping shape the future through high-level global research. To date, over 350 graduates of the program have gone on to positions as general managers, chief marketing officers, executive vice presidents, senior vice presidents, and vice presidents.     Alumna Crystal Sai, executive director and chief of staff for global online at Estée Lauder, shared how much Kanlian encouraged her and made a difference in her education at FIT and her career. “Professor Kanlian was always my biggest cheerleader and support system,” Sai said. “And not just to me—he was that for all of the students in our graduating class. I’ve always admired and have been fascinated by his commitment to the success of this program and to the success of each and every one of us in our careers.”     In his own comments, Kanlian used a quote from President John F. Kennedy to explain the foundation of the CFMM program: “‘Leadership and learning are indispensable to one another.’ I had this in mind as the blueprint for an industry think tank at FIT in my first meeting with President Brown 22 years ago. We spoke about an opportunity to train the next generation of leadership for a dynamic, creative industry. With her enduring support, and the partnership of industry, beauty has become an integral part of the Fashion Institute’s DNA.”     The surprise of the evening came when Levy announced The Fragrance Foundation FIT Diversity Scholarship, a $100,000 academic award that will benefit FIT’s Cosmetics and Fragrance Marketing programs on the undergraduate and graduate levels. Scholarships for both programs will be awarded based on their application criteria. This gift demonstrates TFF’s commitment to diversity and education.     Guests of the event left with beautiful bags designed by FIT alumna, fashion designer, and artist Rebecca Moses, whose original drawings are being donated to FIT by The Fragrance Foundation.

As a crescent moon rose above the campus on November 8, the Undergraduate Student Government (USG) at Stony Brook hosted its fourth annual Light the Brook event, continuing a tradition of lighting the Academic Mall as the fall semester winds down.     On a stage set by the fountain, several student and university leaders addressed a large group of attendees who were treated to brownies and hot chocolate, all gathered to celebrate the Seawolf community.     Light the night group All photos by John Griffin Anne Green ‘22, an environmental design major in the Honors College and chief of staff of the USG, welcomed the crowd and kicked off the event.     “Light the Brook instills a sense of community and belonging,” she said. “How different this semester has been with the vibrant energy that comes with being back in person. We aim to connect the ties of diversity among the student body and represent how we are all connected every day.”     Stony Brook President Maurie McInnis, accompanied by her Labradoodle, Angus, took the podium next.     “Last year Light the Brook was one of the few in-person events we had,” said President McInnis. “I can’t tell you how great it feels to see so many students gathered here tonight to honor the spirit of Stony Brook. Tonight we celebrate being Seawolves and being together.”     “This is the largest crowd we’ve had since this event began,” added Rick Gatteau, vice president for student affairs. “It’s a pleasure being here with you as we bring life and Stony Brook pride back to campus.”     USG President Manjot Singh, civil engineering ’22, described the event as “encompassing the essence of Stony Brook at this time of year,” noting that it was expanded this year.     “Light the Brook provides a sense of reflection on how we have all shined and persevered through the last two years,” said Singh. “This year is extremely special, because we expanded it to include a total of 75 trees and light posts throughout the Academic Mall, many more than in previous years. And we included sustainable solar options as well.”     Attendees were also treated to performances by the Stony Brook Vocalists, a co-ed a cappella group; Jubilé Latino, a Latinx-Afro-infused dance team; and the Seawolves Marching Band.     Cheryl Chambers, associate dean of students/director of multicultural affairs, described the event as a time to recognize our diversity and remember all that unites us.     “Tonight is a testament to how the Stony Brook community has endured,” she said. “As we light the brook, we should also remember to be a light to each other.”     — Robert Emproto

The Stony Brook University Program in Public Health presents a conversation to answer your questions and learn about updates for both COVID and flu vaccines.     Register now for this free Zoom webinar on Tuesday, November 16, at 7 pm, featuring Gregson Pigott, MD, MPH, Commissioner of the Suffolk County Department of Health Services, and Lawrence E. Eisenstein, MD, MPH, FACP, Commissioner of the Nassau County Department of Health.     Moderator Lisa Benz Scott, PhD, Director of the Program in Public Health at Stony Brook University     Translator Héctor E. Alcalá, PhD, MPH, Core Faculty, Program in Public Health; Assistant Professor,     Dr. Lawrence E. Eisenstein Dr. Lawrence E. Eisenstein Department of Family, Population and Preventive Medicine, Renaissance School of Medicine, Stony Brook University     Co-Sponsors Suffolk County Department of Health Services Nassau County Department of Health Stony Brook Program in Public Health Department of Family, Population and Preventive Medicine, Renaissance School of Medicine at Stony Brook University     With support from the Stony Brook University Alumni Association

More than 70 million people worldwide suffer from stuttering. Without intervention, many of these individuals endure this communication disorder for their entire lives. Even so, intervention therapies may not be accessible as they can be considered out-of-pocket expenses and not always covered by insurance. In a lifetime, the stuttering population is disproportionately at risk for heightened anxiety, insecurity and isolation. This life-long speech disorder stigmatizes its victims as socially inept. Personally and professionally, these individuals are limited by a fluency issue that is out of their control.     Today, thanks to Artificial Intelligence (AI) and Stony Brook University faculty, people who stutter have the opportunity to build confidence through speech improvement.     Stony Brook University PhD candidate Bhavya Ghai and Professor Klaus Mueller from the Department of Computer Science, have proposed an AI-based script-writing tool: Fluent.     Fluent is the first of its kind. Much of the literature that addresses the intersection of stuttering and AI focuses on a singular facet — stuttering detection. While there is no cure to stuttering, only intervention, this literature looks at diagnosis, not solutions. Fluent addresses the latter.     Through the use of AI, the smart writing tool leverages speech patterns of people that stutter, specifically substitution tendencies. Through this, Fluent creates AI-driven inroads for continuous speech.     Those that stutter engage in many practices to conceal their disfluent speech such as avoiding communication altogether, the use of fillers (“um,” “like,” “so”) and substitution. Speakers enact substitution to replace trigger words with appropriate synonyms. These phonological patterns do not quell stuttering, but they mask inconsistencies in speech. Fluent strives to make these substitutions easier.     Fluent is powered by Active learning (AL), a specialized branch of machine learning (ML). AL is responsible for training ML models through user feedback. Queries prompted by AL aptly determine phonetic sequences that induce stuttering episodes.     “In our context, active learning expedites the process of learning an individual’s unique condition, i.e., the phonetic pattern they might struggle to pronounce,” said Ghai.     Upon starting up Fluent, users are asked to tap into their challenges with stuttering. Fluent immediately asks for user feedback by prompting the user to annotate at minimum five words with their level of difficulty to pronounce through a binary: “easy” or “difficult.” As the inventory of words increases, with the corresponding personalized-annotations, Fluent better adapts to specific user needs.     Through these inquiries, Fluent posits trigger words and replaces them. Synonyms are harnessed from an online database that covers multiple online dictionaries: DataMuse. Accessing a single online thesaurus is reputably unreliable, especially in the case of people who stutter, where certain words are discarded for their pronunciation limitations. The variable index of synonyms provides an expansive phonetic opportunity for Fluent users. These replacements appear in a drop-down list when the user hovers over a highlighted word (which indicates possible difficulty in pronunciation). Users then click on the word that best befits their speech.     Post-evaluation, Fluent expresses a positive trend of accuracy. Fluent’s classifier reports an 80 percent accuracy with limited user interactions. As these interactions increase, so does its accuracy.     Design advancements can be employed to address more subtle and nuanced speech disfluencies. AL has a technological edge because the consistent retraining of the ML model allows for more refined feedback. However, detecting trigger words is not the only solution Fluent provides. Stuttering episodes are not only produced by specific phonological patterns, but also situations, speakers and so on. Future endeavors with Fluent set out to explore the intricacies of situations that can spur a stuttering episode in longitudinal and situational contexts.     “In the long run, we hope that technologies such as Fluent might be integrated as an accessibility feature into popular tools like MS PowerPoint, MS Word, Google Sheets, etc. for a broader impact,” said Ghai.     — Alyssa Dey

The State University of New York (SUNY) system recognized Stony Brook’s Division of Student Affairs with three Outstanding Student Affairs Program awards. The Chief Student Affairs Officers organization from state-operated campuses appoints a panel to review nominations, and this year Stony Brook’s Student Affairs was recognized for its innovative programs and initiatives that have demonstrated a positive impact on students’ development and serve to better student life with unique and practical solutions to common issues.     Students in the award-winning Seawolf Outdoor Adventure Program (SOAP) enjoyed a day of fun kayaking in Southampton. Students in the award-winning Seawolf Outdoor Adventure Program (SOAP) enjoyed a day of fun kayaking in Southampton. Student Accessibility Support Center (SASC) was recognized for its Virtual Proctoring Program: Making Online Exams Accessible, in the International, Multicultural, Cultural, Gender, LGBTQ, Spirituality, Disability, and related category. As classes moved to remote learning due to the COVID-19 pandemic, this change had a significant impact on testing for students with accommodations. The various software used for virtual exam proctoring did not leave room for several types of student accommodations, and to overcome this challenge, SASC implemented a Virtual Proctoring program, using widely available tools such as Zoom and Google Calendar, establishing clear protocols for test-takers and training for virtual proctors, as well as developing a close working relationship with faculty and teaching assistants.      Through this plan, SASC was able to proctor almost 900 exams for students with disabilities since the program was first piloted in Summer 2020. This Virtual Proctoring program showcases the ingenuity of the team who, in this challenging situation, was able to find a solution to successfully administer exams utilizing existing tools to ensure academic integrity and benefit both students and faculty.     Next to shine was the Spring Brook Staycation Program for winning the award category, Student Health, Wellness, Counseling, and related category. When SUNY schools made the difficult decision to cancel the traditional Spring Break week due to the COVID-19 pandemic, Stony Brook implemented Spring Brook Staycation as a way to give students outlets to destress and unwind. Spearheaded by the Center for Prevention and Outreach in collaboration with many other Student Affairs departments, Spring Brook Staycation was a series of fun and engaging activities during the last week of March where students on campus could connect and appreciate what the local community had to offer. Sixty in-person, virtual and hybrid activities were offered the week of March 29, 2021.      Inspired by the vacation packages offered by travel agencies, students were free to choose to participate in as many activities as they desired from the following “staycation packages”: Artsy Adventures, Active Escapes, Entertainment Escapades, Foodie Fun, Environmental Energizers, Games and Playcation, and Relationship Refreshers. Spring Brook Staycation was a huge success with more than 90 percent registered attendance for all 60 activities. Students were able to relax and connect with each other in real time and virtually, all while following health and safety protocols.     Lastly, the Seawolves Outdoor Adventure Program (SOAP) was recognized in the Enrollment Management, Financial Aid, Orientation, Parents, First-year, Other-year, and related category. SOAP was developed by Recreation and Wellness with the goal to increase first-year students’ sense of belonging and connection to the university and support their successful transition into college life. After an initial brainstorming session, SOAP began in Fall 2021 as a pilot program aided by the generous support of two Stony Brook alumni, introducing six outdoor activities from which students could choose to participate: Kayak Adventure, Scenic Boat Tour, Horseback Riding, Outdoor Adventure Course, Yoga and Meditation, and Hiking.     The three-day program was an opportunity to create safe, small and supportive groups of new Seawolves focused on learning about Stony Brook, to participate in team-building activities, and to have the opportunity to go off-campus and experience the beauty of Long Island. In total, more than 400 new students expressed interest in participating in the SOAP program and 60 first-year students — from various backgrounds, majors and geographic locations — were selected to participate. Based on the post-event assessment, the program was highly successful and attained the goals of making students feel more equipped to transition to and navigate their new college environment, engage with a diverse group of students, and build friendships. For instance, 73 percent of participating students said they felt a greater sense of belonging after having gone through the program and that many have found friends and lasting connections.     “These awards reflect the student-centered efforts of our entire team, and I am honored that so many colleagues in the Division of Student Affairs were recognized at the SUNY level for their hard work, creativity and initiative,” said Vice President for Student Affairs Richard Gatteau. “I am immensely proud of the tremendous work done by Student Affairs and their commitment to our students,” he continued.

The last drug designed to more effectively treat dangerous systemic fungal infections, most often affecting immunocompromised patients, was developed more than 20 years ago. Now an interdisciplinary team of investigators from Stony Brook University believe they have identified what may be a new approach toward developing another class of better antifungal agents. By inhibiting an enzyme called sterylglucosidase 1 (Sgl1) in a model of Cryptococcosis, the researchers found infection did not spread. They believe this enzyme can be a target for a new class of antifungal drugs. The research findings are published in Nature Communications.     Current antifungals have many drawbacks for patients, including high toxicity and many drug interactions, so the need for new antifungals remains high. Cryptococcus neoformans is a fungal pathogen that, upon entering the lung and moving into the bloodstream, causes life-threatening meningoencephalitis in susceptible patients and is life-threatening.     The COVID-19 pandemic has placed a sharp lens on the dangers of infections that spread, particularly to the lungs. Cancer patients and other immunocompromised individuals with chronic conditions are much more susceptible to systemic fungal infections such as Cryptococcosis.     Cryptoimage A scanned electron microscopy of a cell of Cryptococcus neoformans showing the “hairs” within the fungal cell that cause disease. Credit: Jeehyun Karen You “Essentially by identifying selective small molecule inhibitors of Sgl1 in an experimental model, we found that the infection failed to spread to the brain and began to be cleared from the lungs within two weeks,” summarized Mike Airola, senior author and assistant professor in the Department of Biochemistry and Cell Biology in the Renaissance School of Medicine at Stony Brook University.     “We believe based on our experimentation that by targeting Sgl1, we can create a new class of antifungal agents against this and possibly other fungal pathogens in order to prevent both primary and secondary infections,” said Nivea Pereira de Sa, first author of the manuscript and post-doctoral fellow in the laboratory of Dr. Del Poeta. “We are taking the next steps to test this approach.”     Airola says that the research team involves a collaboration of scientists at Stony Brook through the Institute of Chemical Biology and Drug Discovery. The team includes microbiologists, cell biologists, immunologists and chemists. Additionally, the groundwork to this finding was led by co-senior author and SUNY Distinguished Professor Dr. Maurizio Del Poeta, an internationally recognized expert in fungal disease. His lab demonstrated that Sgl1 is a fungal specific protein, and when mutated, the fungus is non-pathogenic.     The research team presented co-crystal structures of Sgl1 with two inhibitors. By combining traditional medicinal chemistry with computational approaches, they were able to unravel how these anti-Sgl1 compounds interact with the enzyme.     In future research, they expect to develop new derivatives of these inhibitors to see if a complete clearance of infection can occur.

Lia Strait — the URECA researcher of the month for November 2021 — is a senior majoring in biomedical engineering who has been doing research since freshman year under the mentorship of Mei Lin (Ete) Chan and Clinton Rubin from the Department of Biomedical Engineering and the Center for Biotechnology. Earlier this year, Strait also began working on a collaborative mechanobiology research project with Chan, Rubin and Stella Tsirka, from the Department of Pharmacological Sciences, on “The Effect of Low-intensity Vibration Therapy Decreases Levels of Inflammatory Proteins in the Brain in Mouse Model.” Her work on this project was supported this past summer through the URECA Summer – PSEG Explorations in STEM programs, and was presented at the virtual 2021 Summer Symposium. This research will be the basis of her senior departmental honors thesis. Strait plans to pursue a PhD in bioengineering, focusing on mechanobiology.      Strait also worked as a research assistant for Lahara Bio, a start-up biotechnology company, and was involved in her sophomore year in a Vertically Integrated Projects (VIP) team, where she worked on designing and developing Roflex, a motion sensing athletic smartwatch, which she presented at Stony Brook’s WolfieTank pitch competition in 2020. Strait has served as a teaching assistant for BME 205: Clinical Challenges of the 21st Century in Spring 2020 and as a peer tutor for the Academic Success and Tutoring Center in 2021. She also dedicates much of her time to the Stony Brook Equestrian Team, serving currently as president (and formerly as secretary); and is an avid cyclist. She is from Salt Point, NY.

Stony Brook’s annual One Book, One Community program is a fun and innovative way to unite the university and neighboring communities through shared reading and conversation. 2021’s reading is Interior Chinatown by Charles Yu.      Kara Wang Actress Kara Wang Join the panelists in a moderated conversation — Why Representation Matters: Panel Discussion Featuring Actress Kara Wang — based on their expertise and experiences that are tied to themes in the book. The event will be held on Wednesday, November 10, at 6 pm in the Student Activities Center Auditorium. Topics may include race, identity, immigration, inclusivity, representation in pop culture and a variety of fields, and racialized experiences. Judi Brown Clarke, vice president for equity & inclusion and chief diversity officer, will present opening remarks.     This event is free and open to the public.     Register today     Panelists include:     Dr. Edward Sun is a gastroenterologist at Stony Brook Hospital who also researches ways to improve patient access to as well as quality of care.  Dr. Amy Lu is a scientist who studies the relationship between hormones and behavior in non-human primates. Rev. Steven Kim is the pastor at Setauket Methodist.  Kara Wang is a bilingual Chinese American actress who has returned to Los Angeles after five years of working in Asia. She can currently be seen recurring on Freeform’s Good Trouble and Amazon’s Goliath. She will next be seen on the big screen in the highly anticipated sequel Top Gun: Maverick. A pre-event reception with hors d’oeuvres will be held from 5 pm to 6 pm in the Student Activities Center Sculpture Garden (Rain location: Student Activities Center, Room 169).      For more information about the program, schedule of events and how to obtain a free copy of Interior Chinatown, please visit stonybrook.edu/onebook.

7 students ambassadors have been appointed for 2021-2022. From left to right, Hyein Lee, Seungmin Lee, Makusha Leeroy, Ratanak Rin, Bhavika Punjabi, and Yena Kwon. They will be introducing our school for the next year. Shout out to ambassadors!!!

Stony Brook University Hospital received the American Heart Association/American Stroke Association’s Gold Plus Get With The Guidelines® – Stroke Award with Target: Stroke Elite Plus Honor Roll and Target: Type 2 Diabetes Honor Roll. Stony Brook Southampton Hospital received the Gold Plus Get With The Guidelines® – Stroke Quality Achievement Award with Honor Roll Elite and Target: Type 2 Diabetes Honor Roll. These awards recognize Stony Brook Medicine’s commitment to ensuring that stroke patients receive the most appropriate treatment according to nationally recognized, research-based guidelines based on the latest scientific evidence.     Stony Brook University Hospital and Southampton Hospital each earned these awards by meeting specific quality achievement measures for the diagnosis and treatment of stroke patients at a set level for a designated period. These measures include evaluation of the proper use of medications and other stroke treatments aligned with the most up-to-date, evidence-based guidelines with the goal of speeding recovery and reducing mortality and disability for stroke patients. Before discharge, patients should also receive education on managing their health, scheduling a follow-up visit, as well as other care transition interventions. For recognition criteria visit this link.     “I am proud to join a healthcare system worthy of the American Heart and Stroke Association’s Get With The Guidelines® award,” said Dr. Hal Paz, executive vice president, Health Sciences, Stony Brook University. “These designations show Stony Brook Medicine’s commitment to delivering the best possible care to stroke patients across Long Island.”     Stony brook university hospital“We’re proud to have received these awards for so many consecutive years and glad to have helped improve the health outcomes of thousands of stroke patients by implementing the American Heart Association’s Get With The Guidelines-Stroke initiative,” said Dr. Michael Guido, director of the Stony Brook Neurology Stroke Program and co-director of the Stony Brook Cerebrovascular and Stroke Center at Stony Brook Medicine. “Our success is a result of Stony Brook Medicine’s dedicated team of nurses, technicians, radiology staff and physicians, mobile stroke unit EMTs, and other medical specialists in addition to neurologists and neurosurgeons.”           In May 2018, Stony Brook University Hospital became the first hospital in Suffolk County to achieve Comprehensive Stroke Center (CSC) certification by The Joint Commission — the nation’s oldest and largest standards-setting and accrediting body in healthcare. This is the highest level a stroke center can achieve, and involves a rigorous screening process. The advanced Comprehensive Stroke Center designation indicates the hospital’s ability to receive and treat the most complex stroke cases. As a certified comprehensive stroke center, Stony Brook provides nationally recognized best practices and a level of care few hospitals anywhere can match.      The following year, Stony Brook Medicine launched Long Island’s first and only Mobile Stroke Unit Program designed to provide specialized, life-saving care to people within the critical moments of stroke before they even get to the hospital. This allows for time-sensitive stroke therapies to be administered earlier and allows for the transport of stroke patients directly to the most appropriate hospital for the level of care they require.     Stony Brook University Hospital was also named as one of America’s 100 Best HospitalsTM by Healthgrades for stroke care for the past seven years, from 2016 to 2022.     The Southampton Hospital Stroke Team, from left: (First row) Monina Baldo, RN; Lisa Dellipizzi, RN; Deborah O’Brien, RN; Samantha Pullium, RN (Second Row) Rose Paul, RN; Dr. Darin Wiggins, MD; Janet Woo, RN; Catherine Baccelliere, RN; Olga McAbee, MD The Southampton Hospital Stroke Team, from left: (First row) Monina Baldo, RN; Lisa Dellipizzi, RN; Deborah O’Brien, RN; Samantha Pullium, RN (Second Row) Rose Paul, RN; Dr. Darin Wiggins, MD; Janet Woo, RN; Catherine Baccelliere, RN; Olga McAbee, MD Stony Brook Southampton Hospital has met specific guidelines set by the New York State Stroke Designation Program to be recognized as a Primary Stroke Center. The Audrey and Martin Gruss Heart & Stroke Center is capable of treating acute ischemic stroke with IV t-PA and provides patients comprehensive supportive care.     “We are dedicated to improving the quality of care for our stroke patients by implementing the American Heart Association’s Get With The Guidelines-Stroke initiative,” said Dr. Fredric I. Weinbaum, chief medical officer and chief operating officer, Stony Brook Southampton Hospital. “The tools and resources provided help us track and measure our success in meeting evidenced-based clinical guidelines developed to improve patient outcomes.”      “We are pleased to recognize Stony Brook Southampton Hospital for their commitment to stroke care,” said Dr. Lee H. Schwamm, national chairperson of the American Heart Association’s Quality Oversight Committee and executive vice chair of neurology, director of Acute Stroke Services, Massachusetts General Hospital, Boston, Massachusetts. “Research has shown that hospitals adhering to clinical measures through the Get With The Guidelines quality improvement initiative can often see fewer readmissions and lower mortality rates.”     According to the American Heart Association/American Stroke Association, stroke is the No. 5 cause of death and a leading cause of adult disability in the United States. On average, someone in the U.S. suffers a stroke every 40 seconds and nearly 795,000 people suffer a new or recurrent stroke each year.

In a study that used inorganic, physical and analytical chemistry to mimic respiratory droplets that can carry viruses, researchers demonstrated a mechanism that enables multiple mask materials to be protective. Led by Stony Brook University Professor Amy Marschilok, the study findings suggest that adsorptivity of mask materials is an important feature in providing protection from viruses such as SARS-CoV-2. The paper is published in Applied Materials & Interfaces, a journal of the American Chemical Society.     Studies evaluating dry measurements of particles to test mask breakthrough have been conducted during the 2020-21 pandemic. In contrast, researchers in this investigation used a novel method that involved creating a virus nanoparticle mimic, using functionalized nanoparticles suspended in artificial saliva, then spraying the suspension and providing scientists with a unique wet characterization approach to compare the effectiveness of potential mask materials. Thus, rather than viewing the mask as a simple screen, the study tests the adsorptive properties of the mask materials for trapping virus in saliva droplets.     Masktestingvisual This visual of the mask material testing shows the spray simulation process (top graphic), and implementation of X-ray fluorescence spectroscopy to further measure nanoparticle spread and reach (bottom graphic). Credit: Yelena Belyavina “We recognized the precious nature of the N95 respirators, and therefore decided to compare mask materials that are broadly available and represented a range of technology and manufacturing readiness using the evaluation methodology that we developed,” said Marschilok, co-director of the Institute for Electrochemically Stored Energy, associate professor in the Department of Chemistry and adjunct faculty member, Department of Materials Science and Chemical Engineering. She also has a joint appointment with the U.S. Department of Energy’s Brookhaven National Laboratory (BNL), of which Stony Brook is part of the management team.     The masks ranged from a commercialized N95 product, to a commercially available mask material, and a potential future mask material prepared by Oak Ridge National Laboratory’s Carbon Fiber Technology Facility. Each material was characterized using a variety of methods including scanning electron microscopy and X-ray photoelectron spectroscopy at BNL’s Center for Functional Nanomaterials (CFN).     Wetting properties of the mask materials were quantified by measurements of the contact angle with an artificial saliva. The surface functionalized metal oxide nanoparticle suspension in artificial saliva was sprayed with an airbrush device through the mask material onto a target. The amount of suspension reaching the target was measured using X-ray fluorescence spectroscopy at BNL’s National Synchrotron Light Source-II (NSLS-II).     “Our goal was to develop new approaches to characterize mask materials, investigate the adsorptive properties of the mask and consider dispersion of droplets containing the virus. The mechanism investigated adsorbing or trapping the suspended virus mimic rather than blocking it,” summarized Marschilok.     Marschilok and colleagues found that multiple types of mask materials functioned effectively under the test conditions. When the researchers conducted the same experiments to a target without the use of mask protection even at longer distances, much less protection occurred from the viral particles than in the presence of mask materials — a result that further points toward the protective value of masks against virus exposure.     The authors say further investigation is necessary to determine the stability of mask materials over time and extended use as a protection against viral particles.     The DOE’s Office of Science supported the study, with funding provided by the Coronavirus CARES Act, and method development for preparation of the functionalized COVID-19 virion mimic supported as part of the Center for Mesoscale Transport Properties. The CFN and NSLS-II are both DOE Office of Science User Facilities. The National Institutes of Health funded New York Consortium for the Advancement of Postdoctoral Scholars (IRACDA-NYCAPS) provided additional staff support.

The Stony Brook University community is invited to show its support for all those affected by relationship violence in any form by participating in the Take a Stand/Walk with Me march at 1 pm on Wednesday, Oct. 27, at the SAC Plaza.       The event, hosted by the Center for Prevention and Outreach, will begin with remarks from student leaders, and the march, led by the Spirit of Stony Brook Drummers, will start at approximately 1:05 pm and will last about 30 minutes.       After the march, there will be a brief resource fair on the SAC Plaza that will feature representatives from campus and community resources, as well as interactive elements such as a poster signing where event participants can express messages of support for those impacted by all forms of interpersonal violence.       Contact Christine Szaraz (christine.szaraz@stonybrook.edu) to get involved or with questions about the event.